Ezaki Glico Co., Ltd. is a Silver Partner of the Expo’s Signature Pavilion “EARTH MART” and a Premium Partner of the “Osaka Healthcare Pavilion” at Expo 2025 Osaka, Kansai. As part of its participation in both pavilions, Glico held a press briefing on April 30 to share two key announcements: a newly obtained patent related to its “Cellular-care” research, and the development of “Rice soft candy” for the Expo 2025. At the “Osaka Healthcare Pavilion”, Glico is presenting an exhibition focused on “Cellular-care”. The company has been accelerating research on aging prevention and has announced that it has obtained a patent for demonstrating the senescent cell–removing effect of Persian silk tree. In addition to the details of the research that led to the patent, the briefing also covered the story behind “Rice soft candy”, which is being distributed exclusively at the Signature Pavilion “EARTH MART”. This newsletter provides a summary of the press releases announced today.

① Accelerating Research on Aging Prevention

Glico demonstrates senescent cell removal by Persian silk tree and obtains patent —Discovered from Glico’s Library of 6,000 Curated Ingredients —

Ezaki Glico Co., Ltd. conducted research to identify ingredients that act on the causes of aging, selecting approximately 6,000 candidates from its curated ingredient library, with a focus on those suitable for food applications. As a result, Glico demonstrated that Persian silk tree removes senescent cells (senolysis*1), and has now obtained a Patent (Patent No. 7659690). This marks the first patent in Japan for the removal of senescent cells using Persian silk tree. Moving forward, the Glico Group will continue its research, including validation in humans, to further explore its potential in aging-related applications.

For more information, please visit https://www.glico.com/global/news/46993/.

② Each Piece Encapsulates the Gentle Essence of Rice and a Vision for the Future of Our Planet

Glico develops “Rice soft candy” using rice-derived ingredients To be distributed exclusively inside “EARTH MART” at Expo 2025 Osaka, Kansai from the End of May

Ezaki Glico Co., Ltd. is a Silver Partner of the Expo’s Signature Pavilion “EARTH MART” at Expo 2025 Osaka, Kansai. Under the pavilion’s theme, “Thinking about the lives through eating”, Glico has developed “Rice soft candy” by applying the soft-candy-making technology it has cultivated since its founding—using rice, Japan’s staple food, as the key ingredient. “Rice soft candy” will be offered free of charge to pavilion visitors exclusively within “EARTH MART”, starting from the End of May. The Glico Group will continue to share the value of Japanese food culture with the world and offer new ideas that contribute to “Healthier days, Wellbeing for life”.

For more information, please visit https://www.glico.com/global/news/47011.

*1 Senolysis: Refers to the selective removal of senescent cells. The term is derived from seno (senescence) and lysis (destruction or breakdown).

[Notes of caution]

This document is an English translation of the Japanese original. In the event of any differences or inconsistencies between the Japanese and English versions, the Japanese language version shall take precedence.